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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCEL All Species: 27.27
Human Site: S408 Identified Species: 50
UniProt: Q5QJ74 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5QJ74 NP_001123519.1 424 48195 S408 Y S S R A L H S F G I R D G D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107143 424 48146 S408 Y S S R A L H S F G I R D G D
Dog Lupus familis XP_546476 474 54071 S458 Y S S R A L H S F G I R D G D
Cat Felis silvestris
Mouse Mus musculus Q8C5W3 424 48013 S408 Y S S R A L H S F G I R D G D
Rat Rattus norvegicus Q5PQJ7 424 48027 S408 Y S S R A L H S F G I R D G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505426 448 50738 S432 F S S R A L H S F G I R D G D
Chicken Gallus gallus XP_427094 424 48312 S408 Y S S R A L H S Y G I R D G D
Frog Xenopus laevis Q5U508 522 58770 L484 L K V P G S D L K L S Y Q S S
Zebra Danio Brachydanio rerio Q5U378 521 59024 L482 L K L P G V E L K L T Y T C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610562 459 53124 Y443 R Y P N K Q L Y S Y N I Q S G
Honey Bee Apis mellifera XP_625182 456 52092 L424 M L Y P N K Q L Y R Y N I R N
Nematode Worm Caenorhab. elegans Q9BLB6 253 28846 N238 K V P E K G W N R Q M D Q N G
Sea Urchin Strong. purpuratus XP_795187 436 49499 L420 L R Y P N R F L H N Y K I G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 89 N.A. 97.4 96.9 N.A. 89 89.3 24.3 23.2 N.A. 38.5 37.9 20.7 36.4
Protein Similarity: 100 N.A. 99.7 89 N.A. 99.5 99.5 N.A. 92.1 94 42.5 40.6 N.A. 55.7 58.3 35.3 58.2
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 93.3 0 0 N.A. 0 0 0 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 0 6.6 N.A. 0 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 54 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 8 54 0 62 % D
% Glu: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 8 0 47 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 16 8 0 0 0 54 0 0 0 62 16 % G
% His: 0 0 0 0 0 0 54 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 54 8 16 0 0 % I
% Lys: 8 16 0 0 16 8 0 0 16 0 0 8 0 0 0 % K
% Leu: 24 8 8 0 0 54 8 31 0 16 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 8 16 0 0 8 0 8 8 8 0 8 8 % N
% Pro: 0 0 16 31 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 8 0 0 8 0 0 24 0 0 % Q
% Arg: 8 8 0 54 0 8 0 0 8 8 0 54 0 8 0 % R
% Ser: 0 54 54 0 0 8 0 54 8 0 8 0 0 16 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % T
% Val: 0 8 8 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 47 8 16 0 0 0 0 8 16 8 16 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _